Experiment 139672

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

COCHINMICIN I

Details

PropertyValue
Pharmacology
ENDOTHELIN INHIBITION
OrganismMicrobispora species (THERMOMONOSPORACEAE)
CitationLAM,YKT: WILLIAMS JR,DL: SIGMUND,JM: SANCHEZ,M: GENILLOUD,O: KONG,YL: STEVENS-MILES,S: HUANG,L: GARRITY,GM:. (1992). COCHINMICINS, NOVEL AND POTENT CYCLODEPSIPEPTIDE ENDOTHELIN ANTAGONIST S FROM A MICROBISPORA SP. I. PRODUCTION, ISOLATION, AND CHARACTERIZATION.. 45(11)
Amount utilized
Compound isolated
Dose amount0.24 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionIC50