Experiment 143182

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CHROMAN,TRANS-4-(3-DODECANOYL-2-4-6-TRIHYDROXYPHENYL)-7-HYDROXY-2-(4-HYDROXY-PEHNYL):

Alerts

DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
PHOSPHOLIPASE A2 INHIBITION
OrganismHorsfieldia amygdalina (MYRISTICACEAE)
CitationMIYAKE,A: YAMAMOTO,H: TAKEBAYASHI,Y: IMAI,H: HONDA,K:. (1992). THE NOVEL NATURAL PRODUCT YM-26567-1 [(+)-TRANS-4-(3-DODECANOYL-1,4,6-TRIHYDROXYPHENYL)-7-HYDROXY-2-(4-HYDROXYPHENYL)CHROMAN}: A COMPETITIVE INHIBITOR OF GROUP II PHOSPHOLIPASE A2.. 263(3)
Amount utilized
Compound isolated
DiseaseRABBIT PLATELET WAS USED. THE ACTIVITY WAS INDEPENDENT OF PREINCUBATION TIME.
Dose amount6.7 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50