Experiment 147101
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Streptomyces chrestomyceticus (STREPTOMYCETACEAE) |
| Citation | KATO,S: SHINDO,K: KAWAI,H: ODAWAGA,A: MATSUOKA,M: MOCHIZUKI,J:. (1993). PYRROLOSTATIN, A NOVEL LIPID PEROXIDATION INHIBITOR FROM STREPTOMYCES CHRESTOMYCETICUS. TAXONOMY, FERMENTATION, ISOLATION, STRUCTURE ELUCIDATION AND BIOLOGICAL PROPERTIES.. 46(6) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE INHIBITION OF MALON DIALDEHYDE FORMATION IN RAT BRAIN HOMOGENATE, WITH THE ADDITION OF FE(2+) WAS ASSAYED. THE INHIBITORY ACTIVITY DECREASED FROM 81% T 50% TO 35% WITH DOSES OF 0,1.0 AND 5.0 MICROMOLES OF FE(2+) RESPECTIVELY. |
| Dose amount | 100.0 MICROMOLS |
| Number | 4 |
| Qualitative result | ACTIVE |
| Dose expression | CONC USED |