Experiment 148607

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC FR-901277

Details

PropertyValue
Pharmacology
ELASTASE INHIBITION
OrganismStreptomyces resistomycificus (STREPTOMYCETACEAE)
CitationFUJIE,K: SHINGUH,Y: HATANAKA,H: SHIGEMATSU,N: MURAI,H: FUJITA,T: YAMASHITA,M: OKAMOTO,M: OKUHARA,M:. (1993). FR901277, A NOVEL INHIBITOR OF HUMAN LEUKOCYTE ELASTASE FROM STREPTOMYCES RESISTOMYCIFICUS. PRODUCING ORGANISM, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES.. 46(6)
Amount utilized
Compound isolated
DiseaseVS.HUMAN LEUKOCYTE ELASTASE.
Dose amount0.18 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50