Experiment 154374

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

VINAXANTHONE

Details

PropertyValue
Pharmacology
MAJOR HISTOCOMPATIBILITY PROTEIN BINDING INHIBITION
OrganismPenicillium glabrum (HYPHOMYCETES)
CitationGAMMON,G: CHANDLER,G: DEPLEDGE,P: ELCOCK,C: WRIGLEY,S: MOORE,J: CAMMAROTA,G: SINIGAGLIA,F: MOORE,M:. (1994). A FUNGAL METABOLITE WHICH INHIBITS THE INTERACTION OF CD4 WITH MAJOR HISTOCOMPATIBILITY COMPLEX-ENCODED CLASS II MOLECULES.. 24(4)
Amount utilized
Compound isolated
DiseaseBINDING OF HLA-DRB *0401 TO CD4 ASSAYED.
Dose amount1.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionIC50