Experiment 167485

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

FUSIDIENOL

Details

PropertyValue
Pharmacology
FARNESYL-PROTEIN TRANSFERASE INHIBITION
OrganismFusidium griseum (HYPHOMYCETES)
CitationSINGH,SB: JONES,ET: GOETZ,MA: BILLS,GF: NALLIN-OMSTEAD,M: JENKINS,RG: LINGHAM,RB: SILVERMAN,KC: GIBBS,JB:. (1994). FUSIDIENOL: A NOVEL INHIBITOR OF RAS FARNESYL-PROTEIN TRANSFERASE FROM FUSIDIUM GRISEUM.. 35(27)
Amount utilized
Compound isolated
DiseaseHUMAN RECOMBINANT ENZYME USED.
Dose amount2.7 MICROMOLS
Number3
Qualitative resultACTIVE
Dose expressionIC50