Experiment 173892

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STAUROSPORINE,4'-DEMETHYL-AMINO-4'-5'-DIHYDROXY:

Details

PropertyValue
Pharmacology
IMMUNOSUPPRESSANT ACTIVITY
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationMC ALPINE,JB: KARWOWSKI,JP: JACKSON,M: MULLALLY,MM: HOCHLOWSKI,JE: PREMACHANDRAN,U: BURRES,NS:. (1994). MLR-52, (4'-DEMETHYLAMINO-4',5'-DIHYDROXYSTAUROSPORINE), A NEW INHIBITOR OF PROTEIN KINASE C WITH IMMUNOSUPPRESSIVE ACTIVITY.. 47(3)
Amount utilized
Compound isolated
DiseaseINHIBITS MOUSE MIXEED LYMPHOCYTE MITOGENIC RESPONSE.
Dose amount1.9 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50