Experiment 173893

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STAUROSPORINE,4'-DEMETHYL-AMINO-4'-5'-DIHYDROXY:

Details

PropertyValue
Pharmacology
PROTEIN KINASE C INHIBITION
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationMC ALPINE,JB: KARWOWSKI,JP: JACKSON,M: MULLALLY,MM: HOCHLOWSKI,JE: PREMACHANDRAN,U: BURRES,NS:. (1994). MLR-52, (4'-DEMETHYLAMINO-4',5'-DIHYDROXYSTAUROSPORINE), A NEW INHIBITOR OF PROTEIN KINASE C WITH IMMUNOSUPPRESSIVE ACTIVITY.. 47(3)
Amount utilized
Compound isolated
Dose amount10.0 MCG
Number3
Qualitative resultACTIVE
Per unitML
Dose expressionIC50