Experiment 179467

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

FURAN-2-ONE,5(H): 5-HYDROXY-3-VINYL:

Details

PropertyValue
Pharmacology
PHOSPHOLIPASE A2 INHIBITION
OrganismCalyptella species (TRICHOLOMATACEAE)
CitationLORENZEN,K: ANKE,T: KONETSCHNY-RAPP,S: SCHEUER,W:. (1995). 5-HYDROXY-3-VINYL-2(5H)-FURANONE - A NEW INHIBITOR OF HUMAN SYNOVIAL PHOSPHOLIPASE A2 AND PLATELET AGGREGATION FROM FERMENTATIONS OF A CALYPTELLA SPECIES (BASIDIOMYCETES).. 50(5/6)
Amount utilized
Compound isolated
DiseaseEFFECTS TESTED ON HUMAN CYTOSOLIC PHOSPHOLIPASE A2.
Dose amount<793 MICROMOLS
Number19
Qualitative resultWEAK ACTIVITY
AnimalHUMAN ADULT
Dose expressionIC50