Experiment 182736

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CHROMOPHILONE I,ISO:

Details

PropertyValue
Pharmacology
GP120 BINDING TO CD4+ CELLS INHIBITION
OrganismPenicillium multicolor (HYPHOMYCETES)
CitationMATSUZAKI,K: IKEDA,H: MASUMA,R: TANAKA,H: OMURA,S:. (1995). ISOCHROMOPHILONES I AND II, NOVEL INHIBITORS AGAINST GP120-CD4 BINDING PRODUCED BY PENICILLIUM MULTICOLOR FO-2338. I. SCREENING, TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITY.. 48(7)
Amount utilized
Compound isolated
DiseaseGP120: CD4 BINDING ASSAYED.
Dose amount6.6 MICROMOLS
Number9
Qualitative resultACTIVE
Dose expressionIC50