Experiment 190876

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PESTALOTIOPSIS ANTIBIOTIC RES-1214-2

Details

PropertyValue
Pharmacology
ENDOTHELIN A RECEPTOR BINDING INHIBITION
OrganismPestalotiopsis species (COELOMYCETES)
CitationOGAWA,T: ANDO,K: AOTANI,Y: SHINODA,K: TANAKA,T: TSUKUDA,E: YOSHIDA,M: MATSUDA,Y:. (1995). RES-1214-1 AND -2, NOVEL NON-PEPTIDIC ENDOTHELIN TYPE A RECEPTOR ANTAGONISTS PRODUCED BY PESTALOTIOPSIS SP.. 48(12)
Amount utilized
Compound isolated
DiseaseASSAY MEASURED BINDING OF ENDOTHELIN-1.
Dose amount19.0 MCG
Number5
Qualitative resultWEAK ACTIVITY
Per unitML
Dose expressionIC50