Experiment 190880

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC SCH-58450

Details

PropertyValue
Pharmacology
GERANYLGERANYL-PROTEIN TRANSFERASE INHIBITION
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationPHIFE,DW: PATTON,RW: BERRIE,RL: YARBOROUGH,R: PUAR,MS: PATEL,M: BISHOP,WR: COVAL,SJ:. (1995). SCH 58450, A NOVEL FARNESYL PROTEIN TRANSFERASE INHIBITOR POSSESSING A 6A,12A,: 7,12-DIEPOXYBENZ[A]ANTHRACENE RING SYSTEM.. 36(39)
Amount utilized
Compound isolated
Dose amount740.0 MICROMOLS
Number3
Qualitative resultWEAK ACTIVITY
Dose expressionIC50