Experiment 190971

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DYSIDIOLIDE

Details

PropertyValue
Pharmacology
PROTEIN PHOSPHATASE INHIBITION
OrganismDysidea etheria (DYSIDEIDAE)
CitationGUNASEDERA,SP: MC CARTHY,PJ: KELLY-BORGES,M: LOBKOVSKY,E: CLARDY,J:. (1996). DYSIDIOLIDE: A NOVEL PROTEIN PHOSPHATASE INHIBITOR FROM THE CARIBBEAN SPONGE DYSIDEA ETHERIA DE LAUBENFELS.. 118(36)
Amount utilized
Compound isolated
DiseaseINHIBITED THE DEPHOSPHORYLATION OF P-NITROPHENOL PHOSPHATE BY CDC25A.
Dose amount9.4 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50