Experiment 190988

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

DRIM-7-EN-11-12-OLIDE,6-(1'-CARBOXY-OCTA-TRANS-2'-TRANS-4'-TRANS-6'-TRIENE)-9-HYDROXY:

Details

PropertyValue
Pharmacology
ENDOTHELIN A RECEPTOR BINDING
OrganismAspergillus ustus (HYPHOMYCETES)
CitationHAYES,MA: WRIGLEY,SK: CHETLAND,I: REYNOLDS,EE: AINSWORTH,AM: RENNO,DV: LATIF,MA: CHENG,XM: HUPE,DJ: CHARLTON,P: DOHERTY,AM:. (1996). NOVEL DRIMANE SESQUITERPENE ESTERS FROM ASPERGILLUS USTUS VAR.PSEUDODEDFLECTUS WITH ENDOTHELIN RECEPTOR BINDING ACTIVITY.. 49(6)
Amount utilized
Compound isolated
Dose amount135.0 MICROMOLS
Number4
Qualitative resultWEAK ACTIVITY
AnimalHUMAN ADULT
Dose expressionIC50