Experiment 198546

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ACTINOPLANIC ACID B

Details

PropertyValue
Pharmacology
FARNESYL-PROTEIN TRANSFERASE INHIBITION
OrganismActinoplanes species (ACTINOPLANACEAE)
CitationSINGH,SB: LIESCH,JM: LINGHAM,RB: SILVERMAN,KC: SIGMUND,JM: GOETZ,MA:. (1995). STRUCTURE,CHEMISTRY, AND BIOLOGY OF ACTINOPLANIC ACIDS: POTENT INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE.. 60(24)
Amount utilized
Compound isolated
Dose amount50.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50