Experiment 199231

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MADINDOLINE A

Details

PropertyValue
Pharmacology
INTERLEUKIN-6-RECEPTOR BLOCKER ACTIVITY
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationHAYASHI,M: KIM,YP: TAKAMATSU,S: ENOMOTO,A: SHINOSE,M: TAKAHASHI,Y: TANAKA,H: KOMIYAMA,K: OMURA,S:. (1996). MADINODOLINE, A NOVEL INHIBITOR OF IL-6 ACTIVITY FROM STREPTOMYCES SP.K93-0711. I. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITIES.. 49(11)
Amount utilized
Compound isolated
Dose amount8.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50