Experiment 207440

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CYANOVIRIN N

Details

PropertyValue
Pharmacology
BINDING EFFECT
OrganismNostoc ellipsosporum (NOSTOCACEAE)
CitationBOYD,MR: GUSTAFSON,KR: MC MAHON,JB: SHOEMAKER,RH: O'KEEFE,BR: MORI,T: GULAKOWSKI,RJ: WU,L: RIVERA,MI: LAURENCOT,CM: CURRENS,MJ: CARDELLINA II,JH: BUCKHEIT JR,RW: NARA,PL: PANNELL,LK: SOWDER II,RC: HENDERSON,LE:. (1997). DISCOVERY OF CYANOVIRIN-N, A NOVEL HUMAN IMMUNODEFICIENCY VIRUS-INACTIVATING PROTEIN THAT BINDS VIRAL SURFACE ENVELOPE GLYCOPROTEIN GP120: POTENTIAL APPLICATIONS TO MICROBICIDE DEVELOPMENT.. 41(7)
Amount utilized
Compound isolated
DiseaseBINDS VIRAL SURFACE ENVELOPE GLYCOPROTEIN GP120.
Dose amount2.4 NANOMOLS
Number6
Qualitative resultACTIVE
Dose expressionED50