Experiment 208101

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BUPLEUROSIDE III

Alerts

RESULTS SIGNIFICANT AT P < 0.01 LEVEL.VS.GALACTOSAMINE-INDUCED HEPATOTOXICITY.

Details

PropertyValue
Pharmacology
CYTOPROTECTIVE ACTIVITY
OrganismBupleurum scorzonerifolium (APIACEAE)
CitationMATSUDA,H: MURAKAMI,T: NINOMIYA,K: INADZUKI,M: YOSHIKAWA,M:. (1997). NEW HEPATOPROTECTIVE SAPONINS, BUPLEUROSIDES III, VI, IX, AND XIII, FROM CHINESE BUPLEURI RADIX: STRUCTURE-REQUIREMENTS FOR THE CYTOPROTECTIVE ACTIVITY IN PRIMARY CULTURED RAT HEPATOCYTES.. 7(17)
Amount utilized
Compound isolated
DiseaseHEPATOCYTES FROM MALE WISTAR RATS WERE ISOLATED FOR THIS EXPERIMENT.
Dose amount1.0 MCG
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionCONC USED