Experiment 214182

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

FUSIDIENOL A

Details

PropertyValue
Pharmacology
FARNESYL-PROTEIN TRANSFERASE INHIBITION
OrganismPhoma species (COELOMYCETES)
CitationSINGH,SB: BALL,RG: ZINK,DL: MONAGHAN,RL: POLISHOOK,JD: SANCHEZ,M: PALAEZ,F: SILVERMAN,KC: LINGHAM,RB:. (1997). FUSIDIENOL A: A NOVEL RAS FARNESYL-PROTEIN TRANSFERASE INHIBITOR FROM PHOMA SP.. 62(21)
Amount utilized
Compound isolated
DiseaseVS.RECOMBINANT HUMAN ENZYME.
Dose amount1.8 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50