Experiment 215189

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CYLINDROCARPOL

Details

PropertyValue
Pharmacology
FARNESYL-PROTEIN TRANSFERASE INHIBITION
OrganismCylindrocarpon lucidum (HYPHOMYCETES)
CitationSINGH,SB: BALL,RG: BILLS,GF: CASCALES,C: GIBBS,JB: GOETZ,MA: HOOGSTEEN,K: JENKINS,RG: LIESCH,JM: LINGHAM,RB: SILVERMAN,KC: ZINK,DL:. (1996). CHEMISTRY AND BIOLOGY OF CYLINDROLS: NOVEL INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE FROM CYLINDROCARPON LUCIDUM.. 61(22)
Amount utilized
Compound isolated
Dose amount77.0 MICROMOLS
Number23
Qualitative resultWEAK ACTIVITY
Dose expressionIC50