Experiment 228347

Worktypes

ANTIFERTILITYPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PREGN-2-EN-4-ONE,5-ALPHA: 20(S)-(DIMETHYL-AMINO)-3-(3'-ALPHA-ISO-PROPYL)-LACTAM: (+):

Details

PropertyValue
Pharmacology
ANTIESTROGENIC EFFECT
OrganismPachysandra procumbens (BUXACEAE)
CitationCHANG,LC: BHAT,KPL: PISHA,E: KENNELLY,EJ: FONG,HHS: PEZZUTO,JM: KINGHORN,AD:. (1998). ACTIVITY-GUIDED ISOLATION OF STEROIDAL ALKALOID ANTIESTROGEN-BINDING SITE INHIBITORS FROM PACHYSANDRA PROCUMBENS.. 61(10)
Amount utilized
Compound isolated
DiseaseVS.TAMOXIFEN BINDING.
Dose amount2.8 MICROMOLS
Number5
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50