Experiment 228353

Worktypes

ANTIFERTILITYPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PREGNAN-4-BETA-OL,5-ALPHA: 2-ALPHA-HYDROXY-20(S)-DIMETHYL-AMINO)-3-BETA-PHTHALIMIDO: (+):

Details

PropertyValue
Pharmacology
ANTIESTROGENIC EFFECT
OrganismPachysandra procumbens (BUXACEAE)
CitationCHANG,LC: BHAT,KPL: PISHA,E: KENNELLY,EJ: FONG,HHS: PEZZUTO,JM: KINGHORN,AD:. (1998). ACTIVITY-GUIDED ISOLATION OF STEROIDAL ALKALOID ANTIESTROGEN-BINDING SITE INHIBITORS FROM PACHYSANDRA PROCUMBENS.. 61(10)
Amount utilized
Compound isolated
DiseaseVS.TAMOXIFEN BINDING.
Dose amount6.8 MICROMOLS
Number11
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50