Experiment 23619

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEISOLATION AND IDENTIFICATION OFPHARMACOLOGY OF EXTRACT - IN HUMANSVOUCHER SPECIMEN REPORTED FORQUANTITATIVE DATA

Compounds isolated

GUAIARETIC ACID,NOR-DIHYDRO:

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeORAL
OrganismLarrea tridentata (ZYGOPHYLLACEAE)
CitationSMART,CR: HOGLE,HH: ROBINS,RK: BROOM,AD: BARTHOLOMEW,D:. (1969). AN INTERESTING OBSERVATION ON NORDIHYDROGUAIARETIC ACID(NSC-4291 NDGA) AND A PATIENT WITH MALIGNANT MELANOMA-A PRELIMINARY REPORT.. 53()
Amount utilized
Compound isolated
Disease85 YEAR OLD WHITE MALE WITH MALIGNANT MELANOMA DOSE USED=2-3 CUPS OF TEA DAILY(7-8 GM PLANT/QUART) NO OTHER MEDICATION-REFUSED SURGICAL TREATMENT 4 MONTHS TREATMENT INDUCED ALMOST COMPLETE REMISSION
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionDOSE
ExtractHOT H2O EXT