Experiment 245113

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

HEMIASTERLIN A

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismAuletta species (AXINELLIDAE)
CitationGAMBLE,WR: DURSO,NA: FULLER,RW: WESTERGAARD,CK: JOHNSON,TR: SACKETT,DL: HAMEL,E: CARDELLINA II,JH: BOYD,MR:. (1999). CYTOTOXIC AND TUBULIN-INTERACTIVE HEMIASTERLINS FROM AULETTA SP. AND SIPHONOCHALINA SPP. SPONGES.. 7(8)
Amount utilized
Compound isolated
DiseaseVS.HUMAN TUMOR CELL LINES NCI-H460.
Dose amount0.1 NG
Number15
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Per unitML
Dose expressionIC50