Experiment 248757
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Phomopsis species (COELOMYCETES) |
| Citation | WRIGLEY,SK: SADEGHI,R: BAHL,S: WHITING,AJ: AINSWORTH,AM: MARTIN,SM: KATZER,W: FORD,R: KAU,DA: ROBINSON,N: HAYES,MA: ELCOCK,C: MANDER,T: MOORE,M:. (1999). A NOVEL(6S)-4,6-DIMETHYLDODECA-2E,4E-DIENOYL ESTER OF PHOMALACTONE AND RELATED ALPHA-PYRONE ESTERS FROM A PHOMOPSIS SP. WITH CYTOKINE PRODUCTION INHIBITORY ACTIVITY.. 52(10) |
| Amount utilized | |
| Compound isolated | |
| Disease | VS.LPS-INDUCED TNF ALPHA PRODUCTION IN U937 CELLS. |
| Dose amount | 0.08 MICROMOLS |
| Number | 2 |
| Qualitative result | STRONG ACTIVITY |
| Animal | CELL CULTURE |
| Dose expression | IC50 |