Experiment 249421

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC TMC-66

Details

PropertyValue
Pharmacology
SAIALOGLYCOPROTEIN RECEPTOR DECREASE
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationASAI,Y: NONAKA,N: SUZUKI,S: NISHIO,M: TAKAHASHI,K: SHIMA,H: OHMOARI,K: OHNUKI,T: KOMATSUBARA,S:. (1999). TMC-66, A NEW ENDOTHELIN CONVERTING ENZYME INHIBITOR PRODUCED BY STREPTOMYCES SP. A5008.. 52(7)
Amount utilized
Compound isolated
DiseaseVS.RAT-LUNG.
Dose amount2.9 MICROMOLS
Number2
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50