Experiment 249486

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

GLIOCLADIUM ANTIBIOTIC TMC-171-B

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismGliocladium species (HYPHOMYCETES)
CitationKOHNO,J: ASAI,Y: NISHIO,M: SAKURAI,M: KAWANG,K: HIRAMATSU,H: KAMEDA,N: KISHI,N: OKUDA,T: KOMATSUBARA,S:. (1999). TMC-171A, B, C AND TMC-154, NOVEL POLYKETIDE ANTIBIOTICS PRODUCED BY GLIOCLADIUM SP. TC 1304 AND TC 1282.. 52(12)
Amount utilized
Compound isolated
DiseaseVS.U937 HUMAN HISTIOCYTIC LYMPHOMA.
Dose amount8.0 MICROMOLS
Number20
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50