Experiment 254841

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

PACHYSANDRINE B,(+):PREGNANE,5-ALPHA: 20(S)-(DIMETHYL-AMINO)-3-ALPHA-(METHYL-BENZOYL-AMINO)-11-METHYLENE:PACHYSAMINE H,(+):PREGN-4-ONE,5-ALPHA: 20(S)-(DIMETHYL-AMINO)-16-ALPHA-HYDROXY-3-BETA-(3'-ALPHA-ISO-PROPYL)-LACTAM: (+):

Details

PropertyValue
Pharmacology
ESTRONE SULFATASE INHIBITION
OrganismPachysandra procumbens (BUXACEAE)
CitationCHANG,LC: BHAT,KPL: FONG,HHS: PEZZUTO,JM: KINGHORN,AD:. (2000). NOVEL BIOACTIVE STEROIDAL ALKALOIDS FROM PACHYSANDRA PROCUMBENS.. 56(20)
Amount utilized
Compound isolated
Dose amount>40.0 MICROMOLS
Number10
Qualitative resultINACTIVE
Dose expressionIC50