Experiment 265672

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

PROTOPINE,3-10-DIMETHOXY-N-DEMETHYL-1-8-DIDEHYDRO:PROTOPINE,3-10-DIHYDROXY-N-DEMETHYL-1-8-DIDEHYDRO:PROTOPINE,3-10-DIMETHOXY-N-DEMETHYL-4(5)-8-DIDEHYDRO:PROTOPINE,3-10-DIHYDROXY-N-DEMETHYL-4(5)-8-DIDEHYDRO:

Details

PropertyValue
Pharmacology
DRUG ADDICTION INHIBITION
Administration routeINTRAGASTRIC
OrganismAristolochia constricta (ARISTOLOCHIACEAE)
CitationCAPASSO,A: DE TOMMASI,N: RASTRELLI,L: DE SIMONE,F:. (2000). NEW PROTOPINE ALKALOIDS FROM ARISTOLOCHIA CONSTRICTA REDUCE MORPHINE WITHDRAWAL IN VITRO.. 14(8)
Amount utilized
Compound isolated
DiseaseVS.MORPHINE.
Dose amount0.1 MILLIMOLS
Number4
Qualitative resultACTIVE
AnimalGUINEA PIG
Dose expressionDOSE
GenderMALE