Experiment 273407

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

BETAENONE,10-HYDROXY-18-N-2-NAPHTHYL-N-PHENYL-AMINO:

Details

PropertyValue
Pharmacology
CYCLIN D1-CDK4 INHIBITION ACTIVITY
OrganismMicrosphaeropsis species (COELOMYCETES)
CitationBRAUERS,G: EDRADA,RA: EBEL,R: PROKSCH,P: WRAY,V: BERG,A: GRAFE,U: SCHACHTELE,C: TOTZKE,F: FINKENZELLER,G: MARME,D: KRAUS,J: MUNCHBACH,M: MICHEL,M: BRINGMANN,G: SCHAUMANN,K:. (2000). ANTHRAQUINONES AND BETAENONE DERIVATIVES FROM THE SPONGE-ASSOCIATED FUNGUS MICROSPHAEROPSIS SPECIES: NOVEL INHIBITORS OF PROTEIN KINASES.. 63(6)
Amount utilized
Compound isolated
Dose amount>100 MICROMOLS
Number7
Qualitative resultINACTIVE
Dose expressionIC50