Experiment 275552

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TOXIN TX-4(5-5)

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
N-METHYL-D-ASPARTATE ANTAGONIST ACTIVITY
OrganismPhoneutria nigriventer (CTENIDAE)
CitationDE FIGUEIREDO,SG: DE LIMA,ME: CORDEIRO,MN: DINIZ,CR: PATTEN,D: HALLIWELL,RF: GILROY,J: RICHARDSON,M:. (2001). PURIFICATION AND AMINO ACID SEQUENCE OF A HIGHLY INSECTICIDAL TOXIN FROM THE VENOM OF THE BRAZILIAN SPIDER PHONEUTRIA NIGRIVENTER WHICH INHIBITS NMDA-EVOKED CURRENTS IN RAT HIPPOCAMPAL NEURONES.. 39(2/3)
Amount utilized
Compound isolated
DiseaseVS.N-METHYL-D-ASPARTATE-SUBTYPE.
Dose amount1.0 MICROMOLS
Number5
Qualitative resultACTIVE
AnimalRAT
Dose expressionCONC USED