Experiment 280483

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SKYRIN-6-O-ALPHA-ARABINOFURANOSIDE,(-): (R):SKYRIN-6-O-BETA-XYLOPYRANOSIDE,(-): (R):SKYRIN-6-O-BETA-D-GLUCOPYRANOSIDE,(+): (S):SKYRIN-6-O-BETA-D-GLUCOPYRANOSIDE,(-): (R):

Details

PropertyValue
Pharmacology
CORTICOTROPIN RELEASING HORMONE RECEPTOR BINDING INHIBITION
OrganismHypericum perforatum (CLUSIACEAE)
CitationWIRZ,A: SIMMEN,U: HEILMANN,J: CLAIS,I: MEIER,B: STICHER,O:. (2000). BISANTHRAQUINONE GLYCOSIDES OF HYPERICUM PERFORATUM WITH BINDING INHIBITION TO CHR-1 RECEPTORS.. 55(8)
Amount utilized
Compound isolated
Dose amount1.0 MICROMOLS
Number3
Qualitative resultACTIVE
Dose expressionIC50