Experiment 32738

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

SAFROLE

Details

PropertyValue
Pharmacology
CARCINOGENIC ACTIVITY
Administration routeIN RATION
OrganismSassafras albidum (LAURACEAE)
CitationBORCHERT,P: MILLER,JA: MILLER,EC: SHIRES,TK:. (1973). 1'-HYDROXYSAFROLE, A PROXIMATE CARCINOGENIC METABOLITE OF SAFROLE IN RAT AND MOUSE.. 33()
Amount utilized
Compound isolated
Disease1/18 RATS DEVELOPED LIVER CARCINOMAS AFTER 8.5 MONTHS FEEDING
Dose amount0.5 % OF DIET
Number1
Qualitative resultEQUIVOCAL
AnimalRAT
Dose expressionDOSE
GenderMALE