Experiment 32739

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

SAFROLE

Details

PropertyValue
Pharmacology
CARCINOGENIC ACTIVITY
Administration routeIN RATION
OrganismSassafras albidum (LAURACEAE)
CitationBORCHERT,P: MILLER,JA: MILLER,EC: SHIRES,TK:. (1973). 1'-HYDROXYSAFROLE, A PROXIMATE CARCINOGENIC METABOLITE OF SAFROLE IN RAT AND MOUSE.. 33()
Amount utilized
Compound isolated
Disease4/18 RATS DEVELOPED LIVER CARCINOMA AFTER 11 MONTHS FEEDING
Dose amount0.5 % OF DIET
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionDOSE
GenderMALE