Experiment 331580

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEISOLATION OF A COMPOUND WITH NOVEL STRUCTUREANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CYCLOHEX-2-ENONE,4-5-6-TRIHYDROXY-2-CROTONYL-OXY-METHYL:

Details

PropertyValue
Pharmacology
GLYOXYLASE I INHIBITION
OrganismStreptomyces griseosporeus (STREPTOMYCETACEAE)
CitationTAKEUCHI,T: CHIMURA,H: HAMADA,M: UMEZAWA,H: YOSHIOKA,O: OGUCHI,N: TAKAHASHI,Y: MATSUDA,A:. (1975). A GLYOXALASE I INHIBITOR OF A NEW STRUCTURAL TYPE PRODUCED BY STREPTOMYCES.. 28()
Amount utilized
Compound isolated
Disease65% INHIBITION AFTER 3 MIN PREINCUBATION 91% INHIBITION AFTER 20 MIN PREINCUBATION
Dose amount2.5 MOL
Number4
Qualitative resultACTIVE
Dose expressionCONC USED