Experiment 332336

Worktypes

MECHANISM OF ACTION STUDIEDPHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

MAYTANSINE

Details

PropertyValue
Pharmacology
ANTIMITOGENIC ACTIVITY
OrganismEmpty organism
CitationREMILLARD,S: REBHUN,LI: HOWIE,GA: KUPCHAN,SM:. (1975). ANTIMITOTIC ACTIVITY OF THE POTENT TUMOR INHIBITOR MAYTANSINE.. 189()
Amount utilized
Compound isolated
DiseaseIRREVERSIBLE INHIBITION OF CELL DIVISION MITOTIC APPARATUS DISAPPEARS CONCENTRATION USED WAS 6.0 X 10(-8) M
Dose amount<0.01 MOL
Number1
Qualitative resultACTIVE
Dose expressionDOSE