Experiment 334529

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN HUMANS

Compounds isolated

EMETINE,(-):

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeSC
OrganismEmpty organism
CitationMOERTEL,CG: SCHUTT,AJ: HAHN,RG: REITEMEIER,RJ:. (1974). TREATMENT OF ADVANCED GASTROINTESTINAL CANCER WITH EMETINE (NSC-33669).. 58()
Amount utilized
Compound isolated
DiseaseADVANCED GI CANCER-25 PATIENTS 2 DOSE REGIMENS: 10 MG/KG(TOTAL) IN DIV DOSES/10 DA TOTAL O 15 MG/KG IN DIV DOSES AT 15 DAY INTERVALS NAUSEA,VOMITING,MUSCLE WEAKNESS,EKG CHANGES ELEVATED SERUM CREATINE KINASE LEVELS ONE PATIENT SHOWED INCOMPLETE & EVANESCENT REGRES
Number1
Qualitative resultINACTIVE
AnimalHUMAN ADULT