Experiment 335817

Worktypes

ANTICANCER AND/OR CYTOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MAYTANVALINE

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismMaytenus buchananii (CELASTRACEAE)
CitationKUPCHAN,SM: KOMODA,Y: BRANFMAN,AR: DAILEY JR,RG: ZIMMERLY,VA:. (1974). NOVEL MAYTANSINOIDS. STRUCTURAL INTERRELATIONS AND REQUIREMENTS FOR ANTILEUKEMIC ACTIVITY.. 96()
Amount utilized
Compound isolated
DiseaseED50 I.0 X 10(-5)MCG/ML
Dose amount<0.01 MCG
Number2
Qualitative resultACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionED50