Experiment 335822

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEYIELD IS LESS THAN 50 MGMMASS-SPECTRAL FRAGMENTATION REPORTEDISOLATION OF A COMPOUND WITH NOVEL STRUCTUREPMR SPECTRUM REPORTED

Compounds isolated

MAYTANACINE

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismPutterlickia verrucosa (CELASTRACEAE)
CitationKUPCHAN,SM: BRANFMAN,AR: SNEDEN,AT: VERMA,AK: DAILEY JR,RG: KOMODA,Y: NAGAO,Y:. (1975). NOVEL MAYTANSINOIDS. NATURALLY OCCURRING AND SYNTHETIC ANTILEUKEMIC ESTERS OF MAYTANSINOL.. 97()
Amount utilized
Compound isolated
Dose amount100.0 MCG
Number2
Percent yield130%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS