Experiment 339002

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEYIELD IS MORE THAN 100 MGMABSOLUTE CONFIGURATION DETERMINEDSTEREOCHEMISTRY DETERMINED FORX-RAY CHRYSTALLOGRAPHIC STUDIESISOLATION OF A COMPOUND WITH NOVEL STRUCTUREANTIBIOTIC MARKER CODE. (USE WITH 14XXX MPASPA)

Compounds isolated

ISOXAZOLE ACETIC ACID,ALPHA-S-4-S-5-R-ALPHA-AMINO-3-CHLORO-HYDROXY-4-5-DIHYDRO-5:

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismStreptomyces sviceus (STREPTOMYCETACEAE)
CitationMARTIN,DG: CHIDESTER,CG: MIZSAK,SA: DUCHAMP,DJ: BACZYNSKYJ,L: KRUEGER,WC: WNUK,RJ: MEULMAN,PA:. (1975). THE ISOLATION, STRUCTURE, AND ABSOLUTE CONFIGURATION OF U-43,795, A NEW ANTITUMOR AGENT.. 28()
Amount utilized
Compound isolated
Number1
Qualitative resultACTIVE
AnimalMOUSE
Dose expressionDOSE