Experiment 352269

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SQUALESTATIN S-1

Details

PropertyValue
Pharmacology
SQUALENE SYNTHASE INHIBITION
OrganismEmpty organism
CitationPROCOPIOU,PA: COX,B: KIRK,BE: LESTER,MG: MC CARTHY,AD: SAREEN,M: SHARRATT,PJ: SNOWDEN,MA: SPOONER,SJ: WATSON,NS: WIDDOWSON,J:. (1996). THE SQUALESTATINS: INHIBITORS OF SQUALENE SYNTHASE. ENZYME INHIBITORY ACTIVITIES AND IN VIVO EVALUATION OF C3-MODIFIED ANALOGUES.. 39(7)
Amount utilized
Compound isolated
Dose amount12.0 NANOMOLS
Number2
Qualitative resultACTIVE
Dose expressionIC50