Experiment 352380

Worktypes

PATENT DESCRIBEDPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ANDROGRAPHOLIDE,ISO:ANDROGRAPHOLIDE,14-DEOXY: 12-METHOXY:ANDROGRAPHOLIDEANDROGRAPHOLIDE,14-DEOXY: 11-HYDROXY:ANDROGRAPHOLIDE,14-DEOXY: 12-HYDROXY:ANDROGRAPHOLIDE,12-EPI: 14-METHOXY:ANDROGRAPHOLIDE,14-EPI:

Alerts

BIOLOGICAL ACTIVITY REPORTED HAS BEEN PATENTED.DATA INCOMPLETE - DERIVED FROM AN ABSTRACT.

Details

PropertyValue
Pharmacology
GENE EXPRESSION INHIBITION
OrganismAndrographis paniculata (ACANTHACEAE)
CitationBABISH,JG: MA,XF:. (1996). USE OF ANDROGRAPHOLIDE COMPOUNDS TO INHIBIT EXPRSSION AND PHOSPHORYLATION OF P34CDC2 KINASE, CYCLIN B, AND MOS-ASSOCD. PROTEINS, AND TO TREAT OR PREVENT PATHOGENICITY OF DISEASES.. ()
Amount utilized
Compound isolated
DiseaseINHIBITED THE EXPRESSION AND PHOSPHORYLATION OF P34-KINASE, CYCLIN B AND MOS-ASSOCIATED PROTEINS.
Number3
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED