Experiment 354545

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

QUERCETIN

Alerts

RESULTS SIGNIFICANT AT P < 0.01 LEVEL.REPORTED BIOLOGICAL ACTIVITY IS HIGHLY DOSE-DEPENDENT.

Details

PropertyValue
Pharmacology
RNA SYNTHESIS INHIBITION
OrganismEmpty organism
CitationSATO,M: MIYAZAKI,T: KAMBE,F: MAEDA,K: SEO,H:. (1997). QUERCETIN, A BIOFLAVONOID, INHIBITS THE INDUCTION OF INTERLEUKIN 8 AND MONOCYTE CHEMOATTRACTANT PROTEIN-1 EXPRESSION BY TUMOR NECROSIS FACTOR-ALPHA IN CULTURED HUMAN SYNOVIAL CELLS.. 24(9)
Amount utilized
Compound isolated
DiseaseVS.TNF-ALPHA STIMULATED EXPRESSION OF IL-8 AND MONOCYTE CHEMOATTRACTANT PROTEIN-1 MRNA.
Dose amount50.0 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED