Experiment 365313

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

CHALCONE,2-4-DIMETHOXY-4'-BUTOXY:*

Details

PropertyValue
Pharmacology
TOXICITY ASSESSMENT(QUANTITATIVE)
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationCHEN,M: CHRISTENSEN,SB: ZHAI,L: RASMUSSEN,MH: THEANDER,TG: FROKJAER,S: STEFFANSEN,B: DAVIDSEN,J: KHARAZMI,A:. (1997). THE NOVEL OXYGENATED CHALCONE, 2-4-DIMETHOXY-4'-BUTOXYCHALCONE, EXHIBITS POTENT ACTIVITY AGAINST HUMAN MALARIA PARASITE PLASMODIUM FALCIPARUM IN VITRO AND RODENT PARASITES PLASMODIUM BERGHEI AND PLASMODIUM YOELII IN VIVO.. 176(5)
Amount utilized
Compound isolated
DiseaseANIMALS WERE TREATED ONCE PER DAY FOR 5 DAYS.
Dose amount5.0 GM
Number11
Qualitative resultINACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
GenderFEMALE