Experiment 367452

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

THIOCYANATE,ISO: PHENETHYL:

Details

PropertyValue
Pharmacology
CYTOCHROME P450 INHIBITION
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationNISHIKAWA,A: LEE,IS: UNEYAMA,C: FURUKAWA,F: KIM,CK: KASAHARA,KI: HUH,N: TAKAHASHI,M:. (1997). MECHANISTIC INSIGHTS INTO CHEMOPREVENTIVE EFFECTS OF PHENETHYL ISOTHIOCYANATE IN N-NITROSOBIS(2-OXOPROPYL)AMINE-TREATED HAMSTERS.. 88(12)
Amount utilized
Compound isolated
DiseaseINHIBITED INDUCTION OF CYP 2B1 WHICH ACTIVATES N-NITROSOBIS (2-OXOPROPYL)AMINE.
Dose amount100.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalHAMSTER
Per unitANIMAL
Dose expressionDOSE