Experiment 368754
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IN RATION |
| Organism | Gossypium species (MALVACEAE) |
| Citation | RISCO,CA: CHENOWETH,PJ: LARSEN,RE: VELEZ,J: SHAW,N: TRAN,T: CHASE,CC:. (1993). THE EFFECT OF GOSSYPOL IN COTTONSEED MEAL ON PERFORMANCE AND ON HEMATOLOGICAL AND SEMEN TRAITS IN POSTPUBERTAL BRAHMAN BULLS.. 40(3) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE EFFECTS OF A COTTONSEED MELA DIET CONTG. HIGH LEVELS OF FREE GOSSYPOL ON HEMATOL. TRAITS, INCLUDING ERYTHROCYTE OSMOTIC FRAGILITY AND SEMEN CHARACTERISTICS, WERE EXAMD DURING AN 11-WK PERIOD. EIGHT BRAHMAN BULLS WERE RANDOMLY ASSIGNED TO 1 OF 2 GROUPS. THE CONTROL GROUP WAS FED A MIXT. OF SOYBEAN MEAL AND CORN. THE TREATED GROUP WAS FED A MIXT. OF COTTONSEEDD MEAL AND CORN. BOTH GROUPS WERE ALLOWED HAY CHOIC. THE TREATED GROUP CONSUMED 8.2 G OF FREE GOSSYPOL PER BULL PER DAY. THE PERCENTAGE OF NORMAL SPERMATOZOA WAS LOWER IN THE TREATED THAN IN THE CONTROL GROUP FROM WEEK 5 (49 VS.83%), WHICH WAS PRIMARILY INFLUENCE BY CHANGES IN MID PIECE MORPHOL. IN THE TREATED BULL.S ERYTHROCYTE OSMOTIC FRAGILITY WAS HIGHER IN THE TREATED THAN IN THE CONTROL GROUP OVER THE ENTIRE STUDY PERIOD, ALTHOUGH GROUP VALUES DIVERGED MORE ACUTELY FROM WEEK 7 OF TREATMENT. SPERM MOTILITY WAS LOWER IN TREATED BULLS THAN IN CONTROL BULLS AT WEEK 9 (52 VS. 82%). THESE DATA SUGGEST THAT CONCURRENT DISCERNABLE CHANGES IN BULL ERYTHROCYTE OSMOTIC FRAGILITY AND IN SEMEN CHARACTERISTICS CAN OCCUR FOLLOWING COMMENCEMENT OF A DIET CONTG. 8.2G OF FREE GOSSYPOL PER DAY. |
| Dose amount | 8.2 GM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | BULL |
| Per unit | ANIMAL |
| Dose expression | DOSE |
| Extract | SEEDS |
| Gender | MALE |