Experiment 371788

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MAYUMBINE

Details

PropertyValue
Pharmacology
BENZODIAZEPINE BINDING INHIBITION
OrganismRauvolfia vomitoria (APOCYNACEAE)
CitationAL,J: DEKERMENDJIAN,K: NIELSEN,M: WITT,MR:. (1997). THE HETEROHYOHIMBINE MAYUMBINE BINDS WITH HIGH AFFINITY TO RAT BRAIN BENZODIAZEPINE RECEPTORS IN VITRO.. 11(1)
Amount utilized
Compound isolated
DiseaseINHIBITED 3H-DIAZEPAM BINDING TO THE BENZODIAZEPINE SITES WITHIN THE GABA-A RECEPTOR COMPLEX.
Dose amount76.0 NANOMOLS
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionIC50