Experiment 376381

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CRYPTOLEPINE

Details

PropertyValue
Pharmacology
TOPOISOMERASE II INHIBITION
OrganismEmpty organism
CitationBONJEAN,K: DE PAUW-GILLET,MC: DEFRESNE,MP: COLSON,P: HOUSSIER,C: DASSONNEVILLE,L: BAILY,C: GREIMERS,R: WRIGHT,C: QUETIN-LECLERCQ,J: TITS,M: ANGENOT,L:. (1998). THE DNA INTERCALATING ALKALOID CRYPTOLEPINE INTERFERES WITH TOPOISOMERASE II AND INHIBITS PRIMARILY DNA SYNTHESIS IN B16 MELANOMA CELL.. 37(15)
Amount utilized
Compound isolated
Dose amount0.5 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionCONC USED