Experiment 376385

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CRYPTOLEPINE

Details

PropertyValue
Pharmacology
RNA SYNTHESIS INHIBITION
OrganismEmpty organism
CitationBONJEAN,K: DE PAUW-GILLET,MC: DEFRESNE,MP: COLSON,P: HOUSSIER,C: DASSONNEVILLE,L: BAILY,C: GREIMERS,R: WRIGHT,C: QUETIN-LECLERCQ,J: TITS,M: ANGENOT,L:. (1998). THE DNA INTERCALATING ALKALOID CRYPTOLEPINE INTERFERES WITH TOPOISOMERASE II AND INHIBITS PRIMARILY DNA SYNTHESIS IN B16 MELANOMA CELL.. 37(15)
Amount utilized
Compound isolated
Dose amount3.7 MICROMOLS
Number6
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50