Experiment 380633

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MEVINOLIN

Details

PropertyValue
Pharmacology
ACYL-CO-A:CHOLESTEROL ACYLTRANSERASE INHIBITION
OrganismEmpty organism
CitationFELELRMANN,K: REIMANN,RM: HEROLD,G: STANGE,EF:. (1992). MEVINOLIN, A COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE, SUPPRESSES ENTEROCYTE ESTERIFICAITON OF EXOGENOUS BUT NOT ENDOGENOUS CHOLESTEROL.. 1165(1)
Amount utilized
Compound isolated
Dose amount40.0 MCG
Number1
Qualitative resultWEAK ACTIVITY
AnimalCELL CULTURE
Per unitML
Dose expressionIC50